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Actionable pathways: interactive discovery of therapeutic targets using signaling pathway models

The discovery of actionable targets is crucial for targeted therapies and is also a constituent part of the drug discovery process. The success of an intervention over a target depends critically on its contribution, within the complex network of gene interactions, to the cellular processes responsi...

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Detalles Bibliográficos
Autores principales: Salavert, Francisco, Hidago, Marta R., Amadoz, Alicia, Çubuk, Cankut, Medina, Ignacio, Crespo, Daniel, Carbonell-Caballero, Jose, Dopazo, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987920/
https://www.ncbi.nlm.nih.gov/pubmed/27137885
http://dx.doi.org/10.1093/nar/gkw369