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Actionable pathways: interactive discovery of therapeutic targets using signaling pathway models
The discovery of actionable targets is crucial for targeted therapies and is also a constituent part of the drug discovery process. The success of an intervention over a target depends critically on its contribution, within the complex network of gene interactions, to the cellular processes responsi...
Autores principales: | Salavert, Francisco, Hidago, Marta R., Amadoz, Alicia, Çubuk, Cankut, Medina, Ignacio, Crespo, Daniel, Carbonell-Caballero, Jose, Dopazo, Joaquín |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987920/ https://www.ncbi.nlm.nih.gov/pubmed/27137885 http://dx.doi.org/10.1093/nar/gkw369 |
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