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MutaBind estimates and interprets the effects of sequence variants on protein–protein interactions
Proteins engage in highly selective interactions with their macromolecular partners. Sequence variants that alter protein binding affinity may cause significant perturbations or complete abolishment of function, potentially leading to diseases. There exists a persistent need to develop a mechanistic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987923/ https://www.ncbi.nlm.nih.gov/pubmed/27150810 http://dx.doi.org/10.1093/nar/gkw374 |