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MutaBind estimates and interprets the effects of sequence variants on protein–protein interactions

Proteins engage in highly selective interactions with their macromolecular partners. Sequence variants that alter protein binding affinity may cause significant perturbations or complete abolishment of function, potentially leading to diseases. There exists a persistent need to develop a mechanistic...

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Detalles Bibliográficos
Autores principales:	Li, Minghui, Simonetti, Franco L., Goncearenco, Alexander, Panchenko, Anna R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Web Server issue
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987923/ https://www.ncbi.nlm.nih.gov/pubmed/27150810 http://dx.doi.org/10.1093/nar/gkw374

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