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mCSM-AB: a web server for predicting antibody–antigen affinity changes upon mutation with graph-based signatures
Computational methods have traditionally struggled to predict the effect of mutations in antibody–antigen complexes on binding affinity. This has limited their usefulness during antibody engineering and development, and their ability to predict biologically relevant escape mutations. Here we present...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987957/ https://www.ncbi.nlm.nih.gov/pubmed/27216816 http://dx.doi.org/10.1093/nar/gkw458 |