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Genetic variation in Mycobacterium tuberculosis isolates from a London outbreak associated with isoniazid resistance

BACKGROUND: The largest outbreak of isoniazid-resistant (INH-R) Mycobacterium tuberculosis in Western Europe is centred in North London, with over 400 cases diagnosed since 1995. In the current study, we evaluated the genetic variation in a subset of clinical samples from the outbreak with the hypot...

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Detalles Bibliográficos
Autores principales: Satta, Giovanni, Witney, Adam A., Shorten, Robert J., Karlikowska, Magdalena, Lipman, Marc, McHugh, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988016/
https://www.ncbi.nlm.nih.gov/pubmed/27530812
http://dx.doi.org/10.1186/s12916-016-0659-6