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Mitofusin‐2 knockdown increases ER–mitochondria contact and decreases amyloid β‐peptide production

Mitochondria are physically and biochemically in contact with other organelles including the endoplasmic reticulum (ER). Such contacts are formed between mitochondria‐associated ER membranes (MAM), specialized subregions of ER, and the outer mitochondrial membrane (OMM). We have previously shown inc...

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Detalles Bibliográficos
Autores principales: Leal, Nuno Santos, Schreiner, Bernadette, Pinho, Catarina Moreira, Filadi, Riccardo, Wiehager, Birgitta, Karlström, Helena, Pizzo, Paola, Ankarcrona, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988279/
https://www.ncbi.nlm.nih.gov/pubmed/27203684
http://dx.doi.org/10.1111/jcmm.12863