Methylglyoxal induces cell death through endoplasmic reticulum stress‐associated ROS production and mitochondrial dysfunction

Diabetic retinopathy (DR) and age‐related macular degeneration (AMD) are two important leading causes of acquired blindness in developed countries. As accumulation of advanced glycation end products (AGEs) in retinal pigment epithelial (RPE) cells plays an important role in both DR and AMD, and the...

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Detalles Bibliográficos
Autores principales: Chan, Chi‐Ming, Huang, Duen‐Yi, Huang, Yi‐Pin, Hsu, Shu‐Hao, Kang, Lan‐Ya, Shen, Chung‐Min, Lin, Wan‐Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988286/
https://www.ncbi.nlm.nih.gov/pubmed/27307396
http://dx.doi.org/10.1111/jcmm.12893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988286/
https://www.ncbi.nlm.nih.gov/pubmed/27307396
http://dx.doi.org/10.1111/jcmm.12893

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