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Methylglyoxal induces cell death through endoplasmic reticulum stress‐associated ROS production and mitochondrial dysfunction
Diabetic retinopathy (DR) and age‐related macular degeneration (AMD) are two important leading causes of acquired blindness in developed countries. As accumulation of advanced glycation end products (AGEs) in retinal pigment epithelial (RPE) cells plays an important role in both DR and AMD, and the...
Autores principales: | Chan, Chi‐Ming, Huang, Duen‐Yi, Huang, Yi‐Pin, Hsu, Shu‐Hao, Kang, Lan‐Ya, Shen, Chung‐Min, Lin, Wan‐Wan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988286/ https://www.ncbi.nlm.nih.gov/pubmed/27307396 http://dx.doi.org/10.1111/jcmm.12893 |
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