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The insights of Let‐7 miRNAs in oncogenesis and stem cell potency

The ability of the classic tumour‐suppressive let‐7 family to inhibit carcinogenesis, tumour progression, recurrence and pluripotency of cancer stem cells has generated significant interest in the field of cancer research. Through suppressing and degrading downstream‐targeted mRNAs, let‐7 affected m...

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Detalles Bibliográficos
Autores principales: Sun, Xin, Liu, Jian, Xu, Chongwen, Tang, Shou‐Ching, Ren, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988292/
https://www.ncbi.nlm.nih.gov/pubmed/27097729
http://dx.doi.org/10.1111/jcmm.12861