Cargando…

Autophagy dysfunction and regulatory cystatin C in macrophage death of atherosclerosis

Autophagy dysfunction in mouse atherosclerosis models has been associated with increased lipid accumulation, apoptosis and inflammation. Expression of cystatin C (CysC) is decreased in human atheroma, and CysC deficiency enhances atherosclerosis in mice. Here, we first investigated the association o...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wei, Sultana, Nargis, Siraj, Nabeel, Ward, Liam J, Pawlik, Monika, Levy, Efrat, Jovinge, Stefan, Bengtsson, Eva, Yuan, Xi‐Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988293/
https://www.ncbi.nlm.nih.gov/pubmed/27079462
http://dx.doi.org/10.1111/jcmm.12859