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Chiral enantioresolution of cathinone derivatives present in “legal highs”, and enantioselectivity evaluation on cytotoxicity of 3,4-methylenedioxypyrovalerone (MDPV)

Recently, great interest has been focused on synthetic cathinones since their consumption has increased exponentially. All synthetic cathinones exist as chiral molecules; the biological and/or toxicological properties of cathinones generally differ according to the enantiomers in human body. In this...

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Detalles Bibliográficos
Autores principales: Silva, Bárbara, Fernandes, Carla, Tiritan, Maria Elizabeth, Pinto, Madalena M.M., Valente, Maria João, Carvalho, Márcia, de Pinho, Paula Guedes, Remião, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988346/
https://www.ncbi.nlm.nih.gov/pubmed/27594923
http://dx.doi.org/10.1007/s11419-016-0324-y