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Protein transduction therapy into cochleae via the round window niche in guinea pigs

Cell-penetrating peptides (CPPs) are short sequences of amino acids that facilitate the penetration of conjugated cargoes across mammalian cell membranes, and as such, they may provide a safe and effective method for drug delivery to the inner ear. Simple polyarginine peptides have been shown to ind...

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Detalles Bibliográficos
Autores principales: Takeda, Hiroki, Kurioka, Takaomi, Kaitsuka, Taku, Tomizawa, Kazuhito, Matsunobu, Takeshi, Hakim, Farzana, Mizutari, Kunio, Miwa, Toru, Yamada, Takao, Ise, Momoko, Shiotani, Akihiro, Yumoto, Eiji, Minoda, Ryosei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988354/
https://www.ncbi.nlm.nih.gov/pubmed/27579336
http://dx.doi.org/10.1038/mtm.2016.55