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Genome‐wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis‐regulation of BORCS7, AS3MT, and NT5C2 in the human brain

Chromosome 10q24.32‐q24.33 is one of the most robustly supported risk loci to emerge from genome‐wide association studies (GWAS) of schizophrenia. However, extensive linkage disequilibrium makes it difficult to distinguish the actual susceptibility gene(s) at the locus, limiting its value for improv...

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Detalles Bibliográficos
Autores principales: Duarte, Rodrigo R. R., Troakes, Claire, Nolan, Matthew, Srivastava, Deepak P., Murray, Robin M., Bray, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988385/
https://www.ncbi.nlm.nih.gov/pubmed/27004590
http://dx.doi.org/10.1002/ajmg.b.32445