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In Silico Structure Prediction of Human Fatty Acid Synthase–Dehydratase: A Plausible Model for Understanding Active Site Interactions

Fatty acid synthase (FASN, UniProt ID: P49327) is a multienzyme dimer complex that plays a critical role in lipogenesis. Consequently, this lipogenic enzyme has gained tremendous biomedical importance. The role of FASN and its inhibition is being extensively researched in several clinical conditions...

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Detalles Bibliográficos
Autores principales: John, Arun, Umashankar, Vetrivel, Samdani, A., Sangeetha, Manoharan, Krishnakumar, Subramanian, Deepa, Perinkulam Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988464/
https://www.ncbi.nlm.nih.gov/pubmed/27559295
http://dx.doi.org/10.4137/BBI.S38317