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Mapping cellular processes in the mesenchyme during palatal development in the absence of Tbx1 reveals complex proliferation changes and perturbed cell packing and polarity

The 22q11 deletion syndromes represent a spectrum of overlapping conditions including cardiac defects and craniofacial malformations. Amongst the craniofacial anomalies that are seen, cleft of the secondary palate is a common feature. Haploinsufficiency of TBX1 is believed to be a major contributor...

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Detalles Bibliográficos
Autores principales: Brock, Lara J., Economou, Andrew D., Cobourne, Martyn T., Green, Jeremy B.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988468/
https://www.ncbi.nlm.nih.gov/pubmed/26689739
http://dx.doi.org/10.1111/joa.12425