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Programmed DNA breaks in lymphoid cells: repair mechanisms and consequences in human disease
In recent years, several novel congenital human disorders have been described with defects in lymphoid B‐cell and T‐cell functions that arise due to mutations in known and/or novel components of DNA repair and damage response pathways. Examples include impaired DNA double‐strand break repair, as wel...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988471/ https://www.ncbi.nlm.nih.gov/pubmed/26455503 http://dx.doi.org/10.1111/imm.12547 |