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Programmed DNA breaks in lymphoid cells: repair mechanisms and consequences in human disease

In recent years, several novel congenital human disorders have been described with defects in lymphoid B‐cell and T‐cell functions that arise due to mutations in known and/or novel components of DNA repair and damage response pathways. Examples include impaired DNA double‐strand break repair, as wel...

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Detalles Bibliográficos
Autores principales: Prochazkova, Jana, Loizou, Joanna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988471/
https://www.ncbi.nlm.nih.gov/pubmed/26455503
http://dx.doi.org/10.1111/imm.12547