Galunisertib (LY2157299), a transforming growth factor-β receptor I kinase inhibitor, attenuates acute pancreatitis in rats

Galunisertib (LY2157299), a selective ATP-mimetic inhibitor of TGF-β receptor I (TGF-βRI), is the only known TGF-β pathway inhibitor. In the present study, we investigated the effect of galunisertib on taurocholate (TAC)-induced acute pancreatitis (AP) in rats, and the role of TGF-β and NF-κB signal...

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Detalles Bibliográficos
Autores principales: Liu, X., Yu, M., Chen, Y., Zhang, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2016
Materias:
Clinical Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988481/
https://www.ncbi.nlm.nih.gov/pubmed/27509307
http://dx.doi.org/10.1590/1414-431X20165388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988481/
https://www.ncbi.nlm.nih.gov/pubmed/27509307
http://dx.doi.org/10.1590/1414-431X20165388

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