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New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition

The ubiD/ubiX or the homologous fdc/pad genes have been implicated in the non-oxidative reversible decarboxylation of aromatic substrates, and play a pivotal role in bacterial ubiquinone biosynthesis1–3 or microbial biodegradation of aromatic compounds4–6 respectively. Despite biochemical studies on...

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Detalles Bibliográficos
Autores principales: Payne, Karl A.P., White, Mark D., Fisher, Karl, Khara, Basile, Bailey, Samuel S., Parker, David, Rattray, Nicholas J.W., Trivedi, Drupad K., Goodacre, Royston, Beveridge, Rebecca, Barran, Perdita, Rigby, Stephen E.J., Scrutton, Nigel S., Hay, Sam, Leys, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988494/
https://www.ncbi.nlm.nih.gov/pubmed/26083754
http://dx.doi.org/10.1038/nature14560