Gefitinib, an EGFR Tyrosine Kinase inhibitor, Prevents Smoke-Mediated Ciliated Airway Epithelial Cell Loss and Promotes Their Recovery

Cigarette smoke exposure is a major health hazard. Ciliated cells in the epithelium of the airway play a critical role in protection against the noxious effects of inhaled cigarette smoke. Ciliated cell numbers are reduced in smokers which weakens host defense and leads to disease. The mechanisms fo...

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Detalles Bibliográficos
Autores principales: Valencia-Gattas, Monica, Conner, Gregory E., Fregien, Nevis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988636/
https://www.ncbi.nlm.nih.gov/pubmed/27532261
http://dx.doi.org/10.1371/journal.pone.0160216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988636/
https://www.ncbi.nlm.nih.gov/pubmed/27532261
http://dx.doi.org/10.1371/journal.pone.0160216

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