Cargando…

Gefitinib, an EGFR Tyrosine Kinase inhibitor, Prevents Smoke-Mediated Ciliated Airway Epithelial Cell Loss and Promotes Their Recovery

Cigarette smoke exposure is a major health hazard. Ciliated cells in the epithelium of the airway play a critical role in protection against the noxious effects of inhaled cigarette smoke. Ciliated cell numbers are reduced in smokers which weakens host defense and leads to disease. The mechanisms fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Valencia-Gattas, Monica, Conner, Gregory E., Fregien, Nevis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988636/
https://www.ncbi.nlm.nih.gov/pubmed/27532261
http://dx.doi.org/10.1371/journal.pone.0160216