Jagged1 Instructs Macrophage Differentiation in Leprosy

As circulating monocytes enter the site of disease, the local microenvironment instructs their differentiation into tissue macrophages (MΦ). To identify mechanisms that regulate MΦ differentiation, we studied human leprosy as a model, since M1-type antimicrobial MΦ predominate in lesions in the self...

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Detalles Bibliográficos
Autores principales: Kibbie, Jon, Teles, Rosane M. B., Wang, Zhiming, Hong, Patrick, Montoya, Dennis, Krutzik, Stephan, Lee, Seung, Kwon, Ohyun, Modlin, Robert L., Cruz, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988718/
https://www.ncbi.nlm.nih.gov/pubmed/27532668
http://dx.doi.org/10.1371/journal.ppat.1005808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988718/
https://www.ncbi.nlm.nih.gov/pubmed/27532668
http://dx.doi.org/10.1371/journal.ppat.1005808

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