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A novel GABA-mediated corticotropin-releasing hormone secretory mechanism in the median eminence

Corticotropin-releasing hormone (CRH), which is synthesized in the paraventricular nucleus (PVN) of the hypothalamus, plays an important role in the endocrine stress response. The excitability of CRH neurons is regulated by γ-aminobutyric acid (GABA)–containing neurons projecting to the PVN. We inve...

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Detalles Bibliográficos
Autores principales: Kakizawa, Keisuke, Watanabe, Miho, Mutoh, Hiroki, Okawa, Yuta, Yamashita, Miho, Yanagawa, Yuchio, Itoi, Keiichi, Suda, Takafumi, Oki, Yutaka, Fukuda, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988769/
https://www.ncbi.nlm.nih.gov/pubmed/27540587
http://dx.doi.org/10.1126/sciadv.1501723