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mRNA poly(A)-tail changes specified by deadenylation broadly reshape translation in Drosophila oocytes and early embryos

Because maturing oocytes and early embryos lack appreciable transcription, posttranscriptional regulatory processes control their development. To better understand this control, we profiled translational efficiencies and poly(A)-tail lengths throughout Drosophila oocyte maturation and early embryoni...

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Detalles Bibliográficos
Autores principales: Eichhorn, Stephen W, Subtelny, Alexander O, Kronja, Iva, Kwasnieski, Jamie C, Orr-Weaver, Terry L, Bartel, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988829/
https://www.ncbi.nlm.nih.gov/pubmed/27474798
http://dx.doi.org/10.7554/eLife.16955