Mechanism of arginine sensing by CASTOR1 upstream of mTORC1

The mechanistic Target of Rapamycin Complex 1 (mTORC1) is a major regulator of eukaryotic growth that coordinates anabolic and catabolic cellular processes with inputs such as growth factors and nutrients, including amino acids(1–3). In mammals, arginine is particularly important and promotes divers...

Descripción completa

Detalles Bibliográficos
Autores principales: Saxton, Robert A., Chantranupong, Lynne, Knockenhauer, Kevin E., Schwartz, Thomas U., Sabatini, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988899/
https://www.ncbi.nlm.nih.gov/pubmed/27487210
http://dx.doi.org/10.1038/nature19079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988899/
https://www.ncbi.nlm.nih.gov/pubmed/27487210
http://dx.doi.org/10.1038/nature19079

Ejemplares similares