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Mechanism of arginine sensing by CASTOR1 upstream of mTORC1
The mechanistic Target of Rapamycin Complex 1 (mTORC1) is a major regulator of eukaryotic growth that coordinates anabolic and catabolic cellular processes with inputs such as growth factors and nutrients, including amino acids(1–3). In mammals, arginine is particularly important and promotes divers...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988899/ https://www.ncbi.nlm.nih.gov/pubmed/27487210 http://dx.doi.org/10.1038/nature19079 |