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Metal-Dependent Regulation of ATP7A and ATP7B in Fibroblast Cultures

Deficiency of one of the copper transporters ATP7A and ATP7B leads to the rare X-linked disorder Menkes Disease (MD) or the rare autosomal disorder Wilson disease (WD), respectively. In order to investigate whether the ATP7A and the ATP7B genes may be transcriptionally regulated, we measured the exp...

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Detalles Bibliográficos
Autores principales: Lenartowicz, Malgorzata, Moos, Torben, Ogórek, Mateusz, Jensen, Thomas G., Møller, Lisbeth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988979/
https://www.ncbi.nlm.nih.gov/pubmed/27587995
http://dx.doi.org/10.3389/fnmol.2016.00068