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Gene expression changes in damaged osteoarthritic cartilage identify a signature of non-chondrogenic and mechanical responses
OBJECTIVES: Joint degeneration in osteoarthritis (OA) is characterised by damage and loss of articular cartilage. The pattern of loss is consistent with damage occurring only where the mechanical loading is high. We have investigated using RNA-sequencing (RNA-seq) and systems analyses the changes th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
W.B. Saunders For The Osteoarthritis Research Society
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989048/ https://www.ncbi.nlm.nih.gov/pubmed/26973327 http://dx.doi.org/10.1016/j.joca.2016.03.007 |