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Cholesterol-dependent Conformational Plasticity in GPCR Dimers

The organization and function of the serotonin(1A) receptor, an important member of the GPCR family, have been shown to be cholesterol-dependent, although the molecular mechanism is not clear. We performed a comprehensive structural and dynamic analysis of dimerization of the serotonin(1A) receptor...

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Detalles Bibliográficos
Autores principales: Prasanna, Xavier, Sengupta, Durba, Chattopadhyay, Amitabha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989139/
https://www.ncbi.nlm.nih.gov/pubmed/27535203
http://dx.doi.org/10.1038/srep31858