Cargando…
Distinguishing autocrine and paracrine signals in hematopoietic stem cell culture using a biofunctional microcavity platform
Homeostasis of hematopoietic stem cells (HSC) in the mammalian bone marrow stem cell niche is regulated by signals of the local microenvironment. Besides juxtacrine, endocrine and metabolic cues, paracrine and autocrine signals are involved in controlling quiescence, proliferation and differentiatio...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989144/ https://www.ncbi.nlm.nih.gov/pubmed/27535453 http://dx.doi.org/10.1038/srep31951 |