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Mfn2 is Required for Mitochondrial Development and Synapse Formation in Human Induced Pluripotent Stem Cells/hiPSC Derived Cortical Neurons

Mitochondria are essential dynamic organelles for energy production. Mitochondria dynamically change their shapes tightly coupled to fission and fusion. Imbalance of fission and fusion can cause deficits in mitochondrial respiration, morphology and motility. Mfn2 (mitofusin 2), a mitochondrial membr...

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Detalles Bibliográficos
Autores principales: Fang, Du, Yan, Shijun, Yu, Qing, Chen, Doris, Yan, Shirley ShiDu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989148/
https://www.ncbi.nlm.nih.gov/pubmed/27535796
http://dx.doi.org/10.1038/srep31462