Cargando…

Mfn2 is Required for Mitochondrial Development and Synapse Formation in Human Induced Pluripotent Stem Cells/hiPSC Derived Cortical Neurons

Mitochondria are essential dynamic organelles for energy production. Mitochondria dynamically change their shapes tightly coupled to fission and fusion. Imbalance of fission and fusion can cause deficits in mitochondrial respiration, morphology and motility. Mfn2 (mitofusin 2), a mitochondrial membr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fang, Du, Yan, Shijun, Yu, Qing, Chen, Doris, Yan, Shirley ShiDu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989148/ https://www.ncbi.nlm.nih.gov/pubmed/27535796 http://dx.doi.org/10.1038/srep31462

Ejemplares similares

Reprogramming of HUVECs into Induced Pluripotent Stem Cells (HiPSCs), Generation and Characterization of HiPSC-Derived Neurons and Astrocytes
por: Haile, Yohannes, et al.
Publicado: (2015)

Comparison and Optimization of hiPSC Forebrain Cortical Differentiation Protocols
por: Muratore, Christina R., et al.
Publicado: (2014)

Astrocytes Attenuate Mitochondrial Dysfunctions in Human Dopaminergic Neurons Derived from iPSC
por: Du, Fang, et al.
Publicado: (2018)

hiPSC-Derived Cells as Models for Drug Discovery
por: Ofir, Rivka
Publicado: (2021)

A mathematical model of hiPSC cardiomyocytes electromechanics
por: Forouzandehmehr, Mohamadamin, et al.
Publicado: (2021)

Characterizing the secretome of licensed hiPSC-derived MSCs
por: Ramos, Yolande F. M., et al.
Publicado: (2022)

A functional hiPSC-cortical neuron differentiation and maturation model and its application to neurological disorders
por: Autar, Kaveena, et al.
Publicado: (2021)

Generation of hiPSC-Derived Skeletal Muscle Cells: Exploiting the Potential of Skeletal Muscle-Derived hiPSCs
por: Metzler, Eric, et al.
Publicado: (2022)

Differentiation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons in Mouse Hippocampal Slice Cultures
por: Hiragi, Toshimitsu, et al.
Publicado: (2017)

Protocol for Tri-culture of hiPSC-Derived Neurons, Astrocytes, and Microglia
por: Ryan, Sean K., et al.
Publicado: (2020)

Development and Dynamic Regulation of Mitochondrial Network in Human Midbrain Dopaminergic Neurons Differentiated from iPSCs
por: Fang, Du, et al.
Publicado: (2016)

Applicability of hiPSC-Derived Neuronal Cocultures and Rodent Primary Cortical Cultures for In Vitro Seizure Liability Assessment
por: Tukker, Anke M, et al.
Publicado: (2020)

Depletion of WFS1 compromises mitochondrial function in hiPSC-derived neuronal models of Wolfram syndrome
por: Zatyka, Malgorzata, et al.
Publicado: (2023)

New considerations for hiPSC-based models of neuropsychiatric disorders
por: Hoffman, Gabriel E., et al.
Publicado: (2018)

The Effect of Uncoated SPIONs on hiPSC-Differentiated Endothelial Cells
por: Salingova, Barbara, et al.
Publicado: (2019)

Considerations in hiPSC-derived cartilage for articular cartilage repair
por: Yamashita, Akihiro, et al.
Publicado: (2018)

Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases
por: Trudler, Dorit, et al.
Publicado: (2021)

α-synuclein pathogenesis in hiPSC models of Parkinson’s disease
por: Baena-Montes, Jara M., et al.
Publicado: (2021)

Gain of PITRM1 peptidase in cortical neurons affords protection of mitochondrial and synaptic function in an advanced age mouse model of Alzheimer’s disease
por: Du, Fang, et al.
Publicado: (2021)

hiPSC-Based Model of Prenatal Exposure to Cannabinoids: Effect on Neuronal Differentiation
por: Miranda, Cláudia C., et al.
Publicado: (2020)

All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors
por: Puppo, Francesca, et al.
Publicado: (2021)

Modeling Movement Disorders via Generation of hiPSC-Derived Motor Neurons
por: Akter, Masuma, et al.
Publicado: (2022)

Engineering hiPSC-CM and hiPSC-EC laden 3D nanofibrous splenic hydrogel for improving cardiac function through revascularization and remuscularization in infarcted heart
por: Guan, Ge, et al.
Publicado: (2021)

pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model
por: Xu, Xiaohong, et al.
Publicado: (2020)

Comparative characterization of human induced pluripotent stem cells (hiPSC) derived from patients with schizophrenia and autism
por: Grunwald, Lena-Marie, et al.
Publicado: (2019)

Chronic Cardiotoxicity Assays Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs)
por: Narkar, Akshay, et al.
Publicado: (2022)

Efficient Differentiation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Mesenchymal Progenitors Into Adipocytes and Osteoblasts
por: Diaz-Hernandez, Martha Elena, et al.
Publicado: (2023)

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
por: Brennand, K, et al.
Publicado: (2015)

Divergent Levels of Marker Chromosomes in an hiPSC-Based Model of Psychosis
por: TCW, Julia, et al.
Publicado: (2017)

Editing the genome of hiPSC with CRISPR/Cas9: disease models
por: Bassett, Andrew R.
Publicado: (2017)

Practical adoption of state-of-the-art hiPSC-cardiomyocyte differentiation techniques
por: Rupert, Cassady E., et al.
Publicado: (2020)

hiPSC-Derived Cardiac Tissue for Disease Modeling and Drug Discovery
por: Li, Junjun, et al.
Publicado: (2020)

An in silico hiPSC-Derived Cardiomyocyte Model Built With Genetic Algorithm
por: Akwaboah, Akwasi D., et al.
Publicado: (2021)

Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids
por: Ramovs, Veronika, et al.
Publicado: (2022)

hiPSC-Derived Cells as Models for Drug Discovery 2.0
por: Ofir, Rivka
Publicado: (2023)

Vascularized hiPSC-derived 3D cardiac microtissue on chip
por: Arslan, Ulgu, et al.
Publicado: (2023)

Vascularized hiPSC-derived 3D cardiac microtissue on chip
por: Arslan, Ulgu, et al.
Publicado: (2023)

Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency
por: Carlessi, L, et al.
Publicado: (2014)

Synaptic and functional alterations in the development of mutant huntingtin expressing hiPSC‐derived neurons
por: Dinamarca, Margarita C., et al.
Publicado: (2022)

Sevoflurane promotes premature differentiation of dopaminergic neurons in hiPSC-derived midbrain organoids
por: Shang, Jia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_98n04njp0v2qoni51mo8oom4jr