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Endosome-mediated endocytic mechanism replenishes the majority of synaptic vesicles at mature CNS synapses in an activity-dependent manner

Whether synaptic vesicles (SVs) are recovered via endosome-mediated pathways is a matter of debate; however, recent evidence suggests that clathrin-independent bulk endocytosis (CIE) via endosomes is functional and preferentially replenishes SV pools during strong stimulation. Here, using brefeldin-...

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Detalles Bibliográficos
Autores principales: Park, Joohyun, Cho, Oh Yeon, Kim, Jung Ah, Chang, Sunghoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989163/
https://www.ncbi.nlm.nih.gov/pubmed/27534442
http://dx.doi.org/10.1038/srep31807