15-Lipoxygenase metabolites of α-linolenic acid, [13-(S)-HPOTrE and 13-(S)-HOTrE], mediate anti-inflammatory effects by inactivating NLRP3 inflammasome

The ratio of ω-6 to ω-3 polyunsaturated fatty acids (PUFAs) appears to be critical in the regulation of various pathophysiological processes and to maintain cellular homeostasis. While a high proportion of dietary intake of ω-6 PUFAs is associated with various inflammatory disorders, higher intake o...

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Detalles Bibliográficos
Autores principales: Kumar, Naresh, Gupta, Geetika, Anilkumar, Kotha, Fatima, Naireen, Karnati, Roy, Reddy, Gorla Venkateswara, Giri, Priyanka Voori, Reddanna, Pallu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989172/
https://www.ncbi.nlm.nih.gov/pubmed/27535180
http://dx.doi.org/10.1038/srep31649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989172/
https://www.ncbi.nlm.nih.gov/pubmed/27535180
http://dx.doi.org/10.1038/srep31649

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