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Dynamics of the formation of a hydrogel by a pathogenic amyloid peptide: islet amyloid polypeptide

Many chronic degenerative diseases result from aggregation of misfolded polypeptides to form amyloids. Many amyloidogenic polypeptides are surfactants and their assembly can be catalysed by hydrophobic-hydrophilic interfaces (an air-water interface in-vitro or membranes in-vivo). We recently demonst...

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Detalles Bibliográficos
Autores principales: Jean, Létitia, Lee, Chiu Fan, Hodder, Peter, Hawkins, Nick, Vaux, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989184/
https://www.ncbi.nlm.nih.gov/pubmed/27535008
http://dx.doi.org/10.1038/srep32124