Cargando…

Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells

Glucagon is one of the main regulators of blood glucose levels and dysfunctional stimulus secretion coupling in pancreatic A-cells is believed to be an important factor during development of diabetes. However, regulation of glucagon secretion is poorly understood. Recently it has been shown that Na(...

Descripción completa

Detalles Bibliográficos
Autores principales: Pedersen, Morten Gram, Ahlstedt, Ingela, El Hachmane, Mickaël F., Göpel, Sven O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989223/
https://www.ncbi.nlm.nih.gov/pubmed/27535321
http://dx.doi.org/10.1038/srep31214