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Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells
Glucagon is one of the main regulators of blood glucose levels and dysfunctional stimulus secretion coupling in pancreatic A-cells is believed to be an important factor during development of diabetes. However, regulation of glucagon secretion is poorly understood. Recently it has been shown that Na(...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989223/ https://www.ncbi.nlm.nih.gov/pubmed/27535321 http://dx.doi.org/10.1038/srep31214 |