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Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells

Glucagon is one of the main regulators of blood glucose levels and dysfunctional stimulus secretion coupling in pancreatic A-cells is believed to be an important factor during development of diabetes. However, regulation of glucagon secretion is poorly understood. Recently it has been shown that Na(...

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Detalles Bibliográficos
Autores principales:	Pedersen, Morten Gram, Ahlstedt, Ingela, El Hachmane, Mickaël F., Göpel, Sven O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989223/ https://www.ncbi.nlm.nih.gov/pubmed/27535321 http://dx.doi.org/10.1038/srep31214

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