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Comparison of gene-based rare variant association mapping methods for quantitative traits in a bovine population with complex familial relationships

BACKGROUND: There is growing interest in the role of rare variants in the variation of complex traits due to increasing evidence that rare variants are associated with quantitative traits. However, association methods that are commonly used for mapping common variants are not effective to map rare v...

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Detalles Bibliográficos
Autores principales: Zhang, Qianqian, Guldbrandtsen, Bernt, Calus, Mario P. L., Lund, Mogens Sandø, Sahana, Goutam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989328/
https://www.ncbi.nlm.nih.gov/pubmed/27534618
http://dx.doi.org/10.1186/s12711-016-0238-5