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Histone H3 and TORC1 prevent organelle dysfunction and cell death by promoting nuclear retention of HMGB proteins

BACKGROUND: How cells respond and adapt to environmental changes, such as nutrient flux, remains poorly understood. Evolutionarily conserved nutrient signaling cascades can regulate chromatin to contribute to genome regulation and cell adaptation, yet how they do so is only now beginning to be eluci...

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Detalles Bibliográficos
Autores principales: Chen, Hongfeng, Workman, Jason J., Strahl, Brian D., Laribee, R. Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989345/
https://www.ncbi.nlm.nih.gov/pubmed/27540414
http://dx.doi.org/10.1186/s13072-016-0083-3