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Improvement of betulinic acid biosynthesis in yeast employing multiple strategies

BACKGROUND: Betulinic acid (BA) is a lupane-type triterpene which has been considered as a promising agent to cure melanoma with no side effects. Considering that BA is naturally produced in small quantities in plants, we previously reported the success in engineering its production in yeast. In the...

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Detalles Bibliográficos
Autores principales: Zhou, Chen, Li, Jing, Li, Changfu, Zhang, Yansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989488/
https://www.ncbi.nlm.nih.gov/pubmed/27534392
http://dx.doi.org/10.1186/s12896-016-0290-9