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Oncolytic virus efficiency inhibited growth of tumour cells with multiple drug resistant phenotype in vivo and in vitro

BACKGROUND: Tumour resistance to a wide range of drugs (multiple drug resistant, MDR) acquired after intensive chemotherapy is considered to be the main obstacle of the curative treatment of cancer patients. Recent work has shown that oncolytic viruses demonstrated prominent potential for effective...

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Detalles Bibliográficos
Autores principales: Goncharova, Elena P., Ruzhenkova, Julia S., Petrov, Ivan S., Shchelkunov, Sergey N., Zenkova, Marina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989492/
https://www.ncbi.nlm.nih.gov/pubmed/27538520
http://dx.doi.org/10.1186/s12967-016-1002-x