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Determination of diclofenac concentrations in human plasma using a sensitive gas chromatography mass spectrometry method

BACKGROUND: A gas chromatography mass spectrometry (GCMS) method for the determination of diclofenac in human plasma has been developed and validated. RESULTS: This method utilizes hexane which is a relatively less toxic extraction solvent compared to heptane and benzene. In addition, phosphoric aci...

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Detalles Bibliográficos
Autores principales: Shah, Iltaf, Barker, James, Naughton, Declan P., Barton, Stephen J., Ashraf, Syed Salman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989500/
https://www.ncbi.nlm.nih.gov/pubmed/27540412
http://dx.doi.org/10.1186/s13065-016-0199-3