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Determination of diclofenac concentrations in human plasma using a sensitive gas chromatography mass spectrometry method
BACKGROUND: A gas chromatography mass spectrometry (GCMS) method for the determination of diclofenac in human plasma has been developed and validated. RESULTS: This method utilizes hexane which is a relatively less toxic extraction solvent compared to heptane and benzene. In addition, phosphoric aci...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989500/ https://www.ncbi.nlm.nih.gov/pubmed/27540412 http://dx.doi.org/10.1186/s13065-016-0199-3 |