N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study

BACKGROUND & OBJECTIVES: Simultaneous administration of phenytoin and isoniazid (INH) in tuberculous meningitis (TBM) or tuberculoma patients with seizures results in higher plasma phenytoin level and thus phenytoin intoxication. N-acetyltransferase 2 (NAT2) enzyme catalyses two acetylation reac...

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Detalles Bibliográficos
Autores principales: Adole, Prashant S., Kharbanda, Parampreet S., Sharma, Sadhna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989831/
https://www.ncbi.nlm.nih.gov/pubmed/27488001
http://dx.doi.org/10.4103/0971-5916.187106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989831/
https://www.ncbi.nlm.nih.gov/pubmed/27488001
http://dx.doi.org/10.4103/0971-5916.187106

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