Cargando…

Sendai virus intra-host population dynamics and host immunocompetence influence viral virulence during in vivo passage

In vivo serial passage of non-pathogenic viruses has been shown to lead to increased viral virulence, and although the precise mechanism(s) are not clear, it is known that both host and viral factors are associated with increased pathogenicity. Under- or overnutrition leads to a decreased or dysregu...

Descripción completa

Detalles Bibliográficos
Autores principales: Peña, José, Chen-Harris, Haiyin, Allen, Jonathan E., Hwang, Mona, Elsheikh, Maher, Mabery, Shalini, Bielefeldt-Ohmann, Helle, Zemla, Adam T., Bowen, Richard A., Borucki, Monica K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989884/
https://www.ncbi.nlm.nih.gov/pubmed/27774301
http://dx.doi.org/10.1093/ve/vew008