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Sendai virus intra-host population dynamics and host immunocompetence influence viral virulence during in vivo passage
In vivo serial passage of non-pathogenic viruses has been shown to lead to increased viral virulence, and although the precise mechanism(s) are not clear, it is known that both host and viral factors are associated with increased pathogenicity. Under- or overnutrition leads to a decreased or dysregu...
Autores principales: | Peña, José, Chen-Harris, Haiyin, Allen, Jonathan E., Hwang, Mona, Elsheikh, Maher, Mabery, Shalini, Bielefeldt-Ohmann, Helle, Zemla, Adam T., Bowen, Richard A., Borucki, Monica K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989884/ https://www.ncbi.nlm.nih.gov/pubmed/27774301 http://dx.doi.org/10.1093/ve/vew008 |
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