Bcl-2, Bcl-xL, and p-AKT are involved in neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma

PURPOSE: Brn3b is a class IV POU domain transcription factor that plays an important role in the development of retinal ganglion cells (RGCs), RGC survival, and particularly axon growth and pathfinding. Our previous study demonstrated that recombinant adenoassociated virus serotype 2 (rAAV-2)–mediat...

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Detalles Bibliográficos
Autores principales: Phatak, Nitasha R., Stankowska, Dorota L., Krishnamoorthy, Raghu R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990101/
https://www.ncbi.nlm.nih.gov/pubmed/27587945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990101/
https://www.ncbi.nlm.nih.gov/pubmed/27587945

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