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Marked Elevation in Plasma Osteoprotegerin Constitutes an Early and Consistent Feature of Cerebral Malaria

Adherence of infected erythrocytes to vascular endothelium causes acute endothelial cell (EC) activation during Plasmodium falciparum infection. Consequently, proteins stored in Weibel-Palade (WP) bodies within EC are secreted into the plasma. Osteoprotegerin (OPG) binds to VWF and consequently is s...

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Detalles Bibliográficos
Autores principales: O’Regan, Niamh, Moxon, Chris, Gegenbauer, Kristina, O’Sullivan, Jamie M., Chion, Alain, Smith, Owen P., Preston, Roger J. S., Brophy, Teresa M., Craig, Alister G., O’Donnell, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Schattauer 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990170/
https://www.ncbi.nlm.nih.gov/pubmed/26766771
http://dx.doi.org/10.1160/TH15-10-0796