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Marked Elevation in Plasma Osteoprotegerin Constitutes an Early and Consistent Feature of Cerebral Malaria
Adherence of infected erythrocytes to vascular endothelium causes acute endothelial cell (EC) activation during Plasmodium falciparum infection. Consequently, proteins stored in Weibel-Palade (WP) bodies within EC are secreted into the plasma. Osteoprotegerin (OPG) binds to VWF and consequently is s...
Autores principales: | O’Regan, Niamh, Moxon, Chris, Gegenbauer, Kristina, O’Sullivan, Jamie M., Chion, Alain, Smith, Owen P., Preston, Roger J. S., Brophy, Teresa M., Craig, Alister G., O’Donnell, James S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Schattauer
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990170/ https://www.ncbi.nlm.nih.gov/pubmed/26766771 http://dx.doi.org/10.1160/TH15-10-0796 |
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