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Intercellular Variability in Protein Levels from Stochastic Expression and Noisy Cell Cycle Processes
Inside individual cells, expression of genes is inherently stochastic and manifests as cell-to-cell variability or noise in protein copy numbers. Since proteins half-lives can be comparable to the cell-cycle length, randomness in cell-division times generates additional intercellular variability in...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990281/ https://www.ncbi.nlm.nih.gov/pubmed/27536771 http://dx.doi.org/10.1371/journal.pcbi.1004972 |