TERT alleviates irradiation-induced late rectal injury by reducing hypoxia-induced ROS levels through the activation of NF-κB and autophagy

The hypoxic microenvironment which is present following irradiation has been proven to promote radiation-induced injury to normal tissues. Previous studies have demonstrated that telomerase reverse transcriptase (TERT) is regulated by hypoxia, and that it plays a protective role in the process of wo...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Qi, Sun, Yong, Lv, Yuefeng, Le, Ziyu, Xin, Yuhu, Zhang, Ping, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990283/
https://www.ncbi.nlm.nih.gov/pubmed/27431814
http://dx.doi.org/10.3892/ijmm.2016.2673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990283/
https://www.ncbi.nlm.nih.gov/pubmed/27431814
http://dx.doi.org/10.3892/ijmm.2016.2673

Ejemplares similares